Control of CXCR2 activity through its ubiquitination on K327 residue

Control of CXCR2 activity through its ubiquitination on K327 residue.

The K327 residue on human CXCR2 (IL-8 high affinity receptor) was identified to modulate agonist-dependent CXCR2 fate, including internalization, ubiquitination, and downstream signaling.