Journal Club: ESCRT-III Acts Downstream of MLKL to Regulate Necroptotic Cell Death and Its Consequen

Phosphatidylserine is exposed prior to loss of cell integrity during necroptosis

ESCRT-III facilitates the shedding of MLKL-damaged plasma membrane from intact cells

ESCRT-III supports cell survival and functions downstream of active MLKL

ESCRT-III allows necroptotic cells to signal surrounding cells