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Journal Club: Bromodomain Protein BRD4 Is a Transcriptional Repressor of Autophagy and Lysosomal Fun
- Molecular Cell 2017 66 (4): 517–532
- 11 sept. 2017
- 1 min de lecture
BRD4 represses a program of autophagy and lysosome genes independently of MiT/TFE
BRD4 de-repression promotes certain types of autophagy, but not others
Nutrient deprivation de-represses BRD4 via AMPK signaling to promote cell survival
Oncoprotein BRD4-NUT is a potent repressor of autophagy and lysosome function
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