Research Highlight: Temozolomide Affects Extracellular Vesicles Released by Glioblastoma Cells

Highlights

Blood of brain tumour patients contains more circulating extracellular vesicles.

Release of extracellular vesicles is enhanced in resistant tumour cells exposed to temozolomide.

Mass spectrometry allows the analysis of the extracellular vesicle cargo.

Temozolomide augments cell adhesion-related proteins in extracellular vesicles.