Journal Club: Hypoxic Induction of Vasorin Regulates Notch1 Turnover to Maintain Glioma Stem-like Ce Highlights Vasorin maintains glioma stem-like cells GSCs) in the hypoxic nicheHIF1α/STAT3 co-activator complex induces Vasorin expression selectively in GSCsVasorin binds to and regulates membranous Notch1 turnoverVasorin expression correlates with glioma aggressiveness
Highlights Vasorin maintains glioma stem-like cells GSCs) in the hypoxic nicheHIF1α/STAT3 co-activator complex induces Vasorin expression selectively in GSCsVasorin binds to and regulates membranous Notch1 turnoverVasorin expression correlates with glioma aggressiveness
