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Journal Club: NF-κB c-Rel Is Crucial for the Regulatory T Cell Immune Checkpoint in Cancer
- Cell 2017; 170(6): 1096–108
- 26 févr. 2018
- 1 min de lecture
Highlights
NF-κB c-Rel regulates the transcriptional landscape of activated Tregs
c-Rel activity in Tregs restricts anti-tumor responses
Chemical c-Rel inhibition reduces melanoma growth and potentiates anti-PD-1 therapy
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