Rechercher
Journal Club: PIP5 Kinases Regulate Membrane Phosphoinositide and Actin Composition for Targeted Gra
- Immunity 2018
- 24 sept. 2018
- 1 min de lecture
Highlights
Immune synapse formation triggers rapid changes in the membrane composition and charge
PIP5K is a molecular sensor of TCR activation and is rapidly depleted at the synapse
PIP5K distribution controls actin recruitment across the immune synapse
Membrane specialization controls accessibility for centrosome docking and secretion
Posts récents
Voir toutNature Cell Biology 2025 Abstract Cells secrete a large variety of extracellular vesicles (EVs) to engage in cell-to-cell and...