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Rechercher

Journal Club: Reciprocal Signaling between Glioblastoma Stem Cells and Differentiated Tumor Cells Pr

  • nbidere
  • 13 nov. 2018
  • 1 min de lecture

  • Differentiated tumor cells cooperate with glioma stem cells to promote tumor growth

  • Differentiated glioma cells secrete BDNF to stimulate NTRK2 on glioma stem cells

  • The neurotrophin BDNF induces glioma stem cells to secrete the VGF neuropeptide

  • VGF promotes survival and growth of both stem-like and differentiated tumor cells

 
 
 
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