Rechercher
Journal Club: O-GlcNAc Transferase Suppresses Inflammation and Necroptosis by Targeting Receptor-Int
- Immunity 2019
- 4 mars 2019
- 1 min de lecture
Highlights
LPS treatment causes a decrease in HBP activity and protein O-GlcNAcylation
OGT deficiency increases activation of innate immune response and necroptosis
O-GlcNAcylation of RIPK3 on T467 inhibits RIPK3-RIPK1 and RIPK3-RIPK3 interaction
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