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Rechercher

Journal Club: Post-translational Modification of OTULIN Regulates Ubiquitin Dynamics and Cell Death

  • Cell Reports 2019, Volume 29 (11): 3652-63
  • 13 janv. 2020
  • 1 min de lecture

The pro-survival function of OTULIN is regulated by post-translational modifications

OTULIN sustains CYLD activity by preventing its phosphorylation and degradation

OTULIN Tyr-56 phosphorylation regulates RIPK1 ubiquitination in necroptosis

DUSP14 is an OTULIN phosphatase that limits necroptosis

 
 
 
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