Journal Club: Post-translational Modification of OTULIN Regulates Ubiquitin Dynamics and Cell Death

The pro-survival function of OTULIN is regulated by post-translational modifications

OTULIN sustains CYLD activity by preventing its phosphorylation and degradation

OTULIN Tyr-56 phosphorylation regulates RIPK1 ubiquitination in necroptosis

DUSP14 is an OTULIN phosphatase that limits necroptosis