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Journal Club: Post-translational Modification of OTULIN Regulates Ubiquitin Dynamics and Cell Death
- Cell Reports 2019, Volume 29 (11): 3652-63
- 13 janv. 2020
- 1 min de lecture
The pro-survival function of OTULIN is regulated by post-translational modifications
OTULIN sustains CYLD activity by preventing its phosphorylation and degradation
OTULIN Tyr-56 phosphorylation regulates RIPK1 ubiquitination in necroptosis
DUSP14 is an OTULIN phosphatase that limits necroptosis
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