top of page
Rechercher

Journal Club: AMPK, a Regulator of Metabolism and Autophagy, Is Activated by Lysosomal Damage via a

  • Molecular Cell 2020
  • 16 mars 2020
  • 1 min de lecture

Lysosomal damage activates AMPK, autophagy, and metabolic and antimicrobial responses


Galectin 9 transduces damage signal to ubiquitin responses via USP9X and TAK1


TAK1 controls AMPK in the physiological context of lysosomal permeability changes


Anti-diabetic drug metformin causes mild lysosomal damage and downstream responses

 
 
 
bottom of page