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Journal Club: Zika Virus Targets Glioblastoma Stem Cells through a SOX2-Integrin αvβ5 Axis
- nbidere
- 23 mars 2020
- 1 min de lecture
Highlights
ZIKV preferentially infects glioblastoma stem cells (GSCs) rather than neural precursor cells
ZIKV kills SOX2 + cells from a diverse array of malignant brain tumors
SOX2 determines susceptibility to ZIKV infection with reduced antiviral responses
Integrin α vβ 5 is a GSC marker and promotes Zika virus infection of GSCs
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