Rechercher
Journal Club: Differentiation Drives Widespread Rewiring of the Neural Stem Cell Chaperone Network
- Molecular Cell 2020
- 27 avr. 2020
- 1 min de lecture
Highlights
NPSC differentiation alters proteostasis strategies by rewiring chaperone network
High TRiC/CCT in NSPCs promotes proteome solubility and stress resilience
sHSP induced in neural progeny detoxify misfolded proteins by spatial sequestration
Widespread decline in TRiC/CCT levels and NSPC proteostasis in brain aging
Posts récents
Voir toutNature Cell Biology 2025 Abstract Cells secrete a large variety of extracellular vesicles (EVs) to engage in cell-to-cell and...