Rechercher
Journal Club: Targeting DGAT1 Ameliorates Glioblastoma by Increasing Fat Catabolism and Oxidative St
- Cell Metabolism 2020
- 29 juin 2020
- 1 min de lecture
Highlights
A high level of DGAT1 is associated with poor survival in individuals with GBM
DGAT1 prevents lipotoxicity in GBM by promoting lipid droplet storage of fatty acids
Inhibiting DGAT1 promotes tumor cell death in GBM via oxidative stress
Targeting DGAT1 strongly suppresses GBM growth in vivo in a mouse model
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