Highlight
Inhibition of the pseudokinase MLKL alters extracellular vesicle release and reduces tumor growth in glioblastoma
iScience 2022
Highlights
The pseudokinase MLKL governs extracellular vesicle release in glioblastoma cells
Blocking MLKL is deleterious to glioblastoma cell expansion in vitro and in vivo
MLKL action in glioblastoma patient cells does not involve necroptosis death
MLKL inhibition potentiates TMZ-induced cell death in glioblastoma patient cells
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