Highlight: Forum in Trends in Cancer
- 13 mars
- 1 min de lecture
Dernière mise à jour : 9 août
A lysosomal requiem for glioblastoma cells
Laura Merlet, Margaux Le Guyon, Julie Gavard
Abstract
Once viewed solely as degradative compartments, lysosomes shape cell fate through signaling, metabolism, and communication. In glioblastoma, their rewiring underlies plasticity, invasion, and resistance to therapies. This forum explores lysosomal dynamics in brain tumors and therapeutic strategies targeting lysosomal vulnerabilities, offering fresh perspectives for precision approaches in this lethal cancer.
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