Journal Club
- nbidere
- 11 mars 2024
- 1 min de lecture
A conserved family of immune effectors cleaves cellular ATP upon viral infection
Cell 2024
Highlights
The CBASS immune effector Cap17 is an ATP nucleosidase
Defensive ATP nucleosidases in bacteria degrade ATP and dATP to block phage
ATP nucleosidases are part of Detocs, a bacterial two-component anti-phage defense system
ATP nucleosidases, common in bacteria, are also found in eukaryotic innate immune factors
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