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Rechercher

Journal Club

  • nbidere
  • 11 mars 2024
  • 1 min de lecture

A conserved family of immune effectors cleaves cellular ATP upon viral infection


Cell 2024


Highlights


  • The CBASS immune effector Cap17 is an ATP nucleosidase

  • Defensive ATP nucleosidases in bacteria degrade ATP and dATP to block phage

  • ATP nucleosidases are part of Detocs, a bacterial two-component anti-phage defense system

  • ATP nucleosidases, common in bacteria, are also found in eukaryotic innate immune factors



 
 
 

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