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Rechercher

Journal Club

  • nbidere
  • 12 avr. 2021
  • 1 min de lecture

A Selective Autophagy Pathway for Phase-Separated Endocytic Protein Deposits

Molecular Cell Volume 80, Issue 5, 3 December 2020, Pages 764-778.e7



Highlights •Ede1 is an intrinsic autophagy receptor for aberrant CME protein assemblies


•Aberrant CME assemblies form by liquid-liquid phase separation


•Liquid-liquid phase separation of Ede1 is important for autophagic degradation


•Ultrastructural view of an LLPS compartment at the PM and within autophagic bodies

 
 
 

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