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Journal Club
- nbidere
- 12 avr. 2021
- 1 min de lecture
A Selective Autophagy Pathway for Phase-Separated Endocytic Protein Deposits
Molecular Cell Volume 80, Issue 5, 3 December 2020, Pages 764-778.e7

Highlights •Ede1 is an intrinsic autophagy receptor for aberrant CME protein assemblies
•Aberrant CME assemblies form by liquid-liquid phase separation
•Liquid-liquid phase separation of Ede1 is important for autophagic degradation
•Ultrastructural view of an LLPS compartment at the PM and within autophagic bodies
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