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Journal Club
- nbidere
- 24 juin 2024
- 1 min de lecture
RNA aggregates harness the danger response for potent cancer immunotherapy
Cell Article| Volume 187, ISSUE 10, P2521-2535.e21, May 09, 2024
Highlights
RNA-LPAs mimic dangerous emboli for lymphoreticular entrapment and systemic immunity
Systemic immunity resets both the peripheral and intratumoral milieu via IFNAR1/RIG-I
RNA-LPAs are safe and effective tumor re-modulators in canines with spontaneous gliomas
RNA-LPAs reprogram the TME and elicit adaptive immunity in human GBM patients
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