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Journal Club
- nbidere
- 8 juin 2021
- 1 min de lecture
Mitocytosis, a migrasome-mediated mitochondrial quality-control process
Cell, VOLUME 184, ISSUE 11, P2896-2910.E13
Highlights
Mild mitochondrial stress triggers disposal of damaged mitochondria by migrasomes
In this process (mitocytosis), motor proteins selectively bind damaged mitochondria
Damaged mitochondria become localized at the cell periphery to facilitate mitocytosis
Mitocytosis maintains mitochondrial quality and viability in neutrophils in vivo
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