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Rechercher

Journal Club

  • nbidere
  • 2 oct. 2023
  • 1 min de lecture

Engineering of dendritic cell bispecific extracellular vesicles for tumor-targeting immunotherapy


Cell Reports Volume 42, ISSUE 10, 113138, October 31, 2023



Highlights


  • Bispecific EVs expressing aCD19 and PD1 are developed by genetic engineering


  • Bispecific EVs target tumor antigen huCD19 and bind PD-L1 within solid tumors


  • Bispecific EVs also target tumor-derived EVs to prevent the formation of premetastatic niche






 
 
 

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