Journal Club: β-Coronaviruses Use Lysosomes for Egress Instead of the Biosynthetic Secretory Pathwaynbidere16 nov. 20201 min de lectureCell 2020Highlights • β-Coronaviruses do not use the biosynthetic secretory pathway to egress• β-Coronaviruses traffic to lysosomes and egress by Arl8b-dependent lysosomal exocytosis• Lysosomes are deacidified, and proteolytic enzymes are inactive in infected cells• Antigen processing and presentation are perturbed in β-coronavirus infection
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