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Serine 165 Phosphorylation of SHARPIN regulates the Activation of NF-κB
- nbidere
- 14 déc. 2020
- 1 min de lecture
Thys et al., iScience 2020

Highlights
Part of SHARPIN is constitutively phosphorylated on S165 in lymphoblastoid cells
SHARPIN S165 phosphorylation governs TNFα-mediated linear ubiquitination of NEMO
Mutation of S165 hinders NF-κB activation
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