Signaling in Oncogenesis, Angiogenesis, and Permeability

RHOJ controls EMT-associated resistance to chemotherapy Nature volume 616, pages 168–175 (2023) Abstract The resistance of cancer cells...

Stiff matrix induces exosome secretion to promote tumour growth Nature Cell Biology volume 25, pages 415–424 (2023) Abstract Tissue ...

Endosomal lipid signaling reshapes the endoplasmicreticulum to control mitochondrial function SCIENCE 16 Dec 2022 Vol 378, Issue 6625...

Congratulations to Mathilde K for her prize at the NET PhD days from Canceropole GO

Structural mechanisms for regulation of GSDMB pore-forming activity Nature (2023) Abstract Cytotoxic lymphocyte-derived granzyme A (GZMA)...

Lysosomal control of senescence and inflammation through cholesterol partitioning Nature Metabolism volume 5 , pages 398–413 (2023) Abstract Whereas cholesterol is vital for cell growth, proliferation, and remodeling, dysregulation of cholesterol metabolism is associated with multiple age-related pathologies. Here we show that senescent cells accumulate cholesterol in lysosomes to maintain the senescence-associated secretory phenotype (SASP). We find that induction of c

Migrasome-derived nanoparticles: the chamber of secrets was opened again FEBS J 2023

Cellular senescence in malignant cells promotes tumor progression in mouse and patient Glioblastoma Nature Communications volume 14,...