Event: Welcome Carolina Nicolau!
Welcome to Dr Carolina Nicolau for her post-doctoral stay with us, under the auspices of UBL, Univ Nantes and SOAP team funding. Carolina...
Event: FSEV 1st meeting in Paris
Check out Gwennan's poster & Julie's talk
Journal Club: Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer
The mutant form of the GTPase KRAS is a key driver of pancreatic cancer but remains a challenging therapeutic target. Exosomes are...
Journal Club: mTOR Controls Mitochondrial Dynamics and Cell Survival via MTFP1
Highlights The mTORC1/4E-BPs/MTFP1/DRP1 axis controls mitochondrial dynamics Active-site mTOR inhibitors induce mitochondrial hyperfusion...
Research Highlight: Pharmacological targeting of apelin impairs glioblastoma growth
Glioblastomas are aggressive brain tumours that contain a subpopulation of highly plastic self-renewing cancer cells. Harford-Wright et...
Event: Welcome to Kilian Trillet!
Welcome to Kilian Trillet to join the team as Engineer Assistant from INSERM.
Journal Club: Oncogenic signaling by Kit tyrosine kinase occurs selectively on the Golgi apparatus i
Gastrointestinal stromal tumors (GISTs) are caused by gain-of-function mutations in the Kit receptor tyrosine kinase. Most primary GIST...
JournalClub: mTORC1 activity repression by late endosomal phosphatidylinositol 3,4-bisphosphate
The mechanistic target of rapamycin complex 1 (mTORC1) regulates cell growth in response to nutrients. Marat et al. found that the lipid...