Signaling in Oncogenesis, Angiogenesis, and Permeability

Highlights The mTORC1/4E-BPs/MTFP1/DRP1 axis controls mitochondrial dynamics Active-site mTOR inhibitors induce mitochondrial hyperfusion...

Glioblastomas are aggressive brain tumours that contain a subpopulation of highly plastic self-renewing cancer cells. Harford-Wright et...

Welcome to Kilian Trillet to join the team as Engineer Assistant from INSERM.

Gastrointestinal stromal tumors (GISTs) are caused by gain-of-function mutations in the Kit receptor tyrosine kinase. Most primary GIST...

The mechanistic target of rapamycin complex 1 (mTORC1) regulates cell growth in response to nutrients. Marat et al. found that the lipid...

Highlights GSCs can be classified into two subgroups based on ASCL1 expression ASCL1 is required for GSCs to undergo neuronal lineage...

Welcome to Audrey Gayraud, Master Student, Universite Nantes, for her training in the lab. She will work on linear ubiquitin assembly...