Targeted activation of ferroptosis in colorectal cancer via LGR4 targeting overcomes acquired drug resistance
Nature Cancer (2024) Abstract Acquired drug resistance is a major challenge for cancer therapy and is the leading cause of cancer...
Stress response silencing by an E3 ligase mutated in neurodegeneration
Nature 2024 Abstract Stress response pathways detect and alleviate adverse conditions to safeguard cell and tissue homeostasis, yet their...

Event: Welcome L3 Pro from Nantes University
1.5 day with SOAP team : workshops, lectures, and more fun
Journal Club: 7-Dehydrocholesterol is an endogenous suppressor of ferroptosis
Nature 2024 Abstract Ferroptosis is a form of cell death that has received considerable attention not only as a means to eradicate...

Journal Club: Motion of VAPB molecules reveals ER–mitochondria contact site subdomains
Nature (2024) Abstract To coordinate cellular physiology, eukaryotic cells rely on the rapid exchange of molecules at specialized...

Event: Highlight by CNRS Biologie
Cancer du cerveau : comment le cholestérol inonde les cellules souches du glioblastome Les cellules souches du glioblastome représentent...

EVENT: NOT THE COVER
NPC1 (aka Elliott) drives Cholesterol (E.T.) to LysosHOME Read the paper to discover that #MALT1 is the bike !!!