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Journal Club
Centrosome amplification mediates small extracellular vesicle secretion via lysosome disruption Current Biology online Feb 2021
Journal Club
Vimentin Coordinates Protein Turnover at the Aggresome during Neural Stem Cell Quiescence Exit Cell Stem Cell Volume 26, Issue 4, 2 April...
Journal Club
NPC1-mTORC1 Signaling Couples Cholesterol Sensing to Organelle Homeostasis and Is a Targetable Pathway in Niemann-Pick Type C...
Journal Club
Targeting PAK4 to reprogram the vascular microenvironment and improve CAR-T immunotherapy for glioblastoma Nature Cancer 2, pages 83–97...
Journal Club:
Nociceptive nerves regulate haematopoietic stem cell mobilization Nature volume 589, pages591–596(2021) Abstract Haematopoietic stem...
Journal Club:
Synergism of TNF-α and IFN-γ Triggers Inflammatory Cell Death, Tissue Damage, and Mortality in SARS-CoV-2 Infection and Cytokine Shock...
Journal Club: Lysosome-targeting chimaeras for degradation of extracellular proteins
Nature volume 584, pages291–297(2020) Abstract ---------------------------------------- The majority of therapies that target individual...
Journal Club: Altered biodistribution of deglycosylated extracellular vesicles through enhanced cell
J Extracell Ves Extracellular vesicles (EVs) from cancer are delivered both proximal and distal organs. EVs are highly glycosylated at...
Journal Club: Integration of innate immune signalling by caspase-8 cleavage of N4BP1
Nature 2020 Mutations in the death receptor FAS1,2 or its ligand FASL3 cause autoimmune lymphoproliferative syndrome, whereas mutations...