Highlight: Julie's presentation at Gordon Research Conference
Autophagy in Stress, Development and Disease Gordon Research Conference Functions of Autophagy Proteins in Lysosome-Dependent and...
Highlight: Nicolas' Lecture at Ubicode
Writing and Editing the Ubiquitin Code Bilbao, Spain 26-27th Feb 2020
Event: Dr Kathryn A Jacobs
Congratulations to Katie for her brilliant defense on the 21st of Feb Jury Committee: Dr Marja Jaattela Dr Servane Tauszig-Delamasure Dr...
Journal Club: The guidance receptor plexin D1 is a mechanosensor in endothelial cells
Shear stress on arteries produced by blood flow is important for vascular development and homeostasis but can also initiate...
Journal Club: Palmitoylation of NOD1 and NOD2 is required for bacterial sensing
NODs require S-palmitoylation to signal The compartmentalization of proteins within the cell is essential for their function. The...
Journal Club: Cell-derived extracellular vesicles can be used as a biomarker reservoir for glioblast
Glioblastoma (GBM) is one of the most aggressive solid tumors for which treatment options and biomarkers are limited. Small extracellular...
Journal Club: Hypoxic Glioma Cell-Secreted Exosomal miR-301a Activates Wnt/β-catenin Signaling and P
Recent evidence suggests that microRNAs (miRNAs) can be released to the extracellular microenvironment and mediate cell-cell...


Journal Club: Post-translational Modification of OTULIN Regulates Ubiquitin Dynamics and Cell Death
The pro-survival function of OTULIN is regulated by post-translational modifications OTULIN sustains CYLD activity by preventing its...


Journal Club: Galectin-3 Coordinates a Cellular System for Lysosomal Repair and Removal
Summary Endomembrane damage elicits homeostatic responses including ESCRT-dependent membrane repair and autophagic removal of damaged...