Journal Club: Cell-derived extracellular vesicles can be used as a biomarker reservoir for glioblast
Glioblastoma (GBM) is one of the most aggressive solid tumors for which treatment options and biomarkers are limited. Small extracellular...
Journal Club: Hypoxic Glioma Cell-Secreted Exosomal miR-301a Activates Wnt/β-catenin Signaling and P
Recent evidence suggests that microRNAs (miRNAs) can be released to the extracellular microenvironment and mediate cell-cell...
Journal Club: Post-translational Modification of OTULIN Regulates Ubiquitin Dynamics and Cell Death
The pro-survival function of OTULIN is regulated by post-translational modifications OTULIN sustains CYLD activity by preventing its...
Journal Club: Galectin-3 Coordinates a Cellular System for Lysosomal Repair and Removal
Summary Endomembrane damage elicits homeostatic responses including ESCRT-dependent membrane repair and autophagic removal of damaged...
Highlight: Exploring drug repurposing to treat glioblastoma
Exploring drug repurposing to treat glioblastoma Dr. Tilmann Kiessling EMBO Communications EMBO - excellence in life sciences MALT1...
Highlight: Paracaspase MALT1 regulates glioma cell survival by controlling endo‐lysosome homeostasis
Abstract Glioblastoma is one of the most lethal forms of adult cancer with a median survival of around 15 months. A potential treatment...
Event: Congrats An !!
An Thys received Helen Starck award from Fondation ARC for her work on Sharpin! Well deserved :-)
Journal Club: Slow phosphorylation of a tyrosine residue in LAT optimizes T cell ligand discriminati
Self–non-self discrimination is central to T cell-mediated immunity. The kinetic proofreading model can explain T cell antigen receptor...