Signaling in Oncogenesis, Angiogenesis, and Permeability

Endothelial transformation in glioblastoma Glioblastoma (GBM) is one of the most aggressive brain tumors. GBM is characterized by...

ABSTRACT Osteoarthritis (OA) is a chronic degenerative disease of articular cartilage that is the most common joint disease worldwide....

Abstract Caspases regulate cell death, immune responses, and homeostasis. Caspase-6 is categorized as an executioner caspase but shows...

Cleavage of the gasdermin proteins to produce pore-forming amino-terminal fragments causes inflammatory cell death (pyroptosis)1....

Highlights NPSC differentiation alters proteostasis strategies by rewiring chaperone network High TRiC/CCT in NSPCs promotes proteome...

KRAS mutant pancreatic ductal adenocarcinoma (PDAC) is characterized by a desmoplastic response that promotes hypovascularity,...

The Hippo and mammalian target of rapamycin complex 1 (mTORC1) pathways are the two predominant growth-control pathways that dictate...