Journal Club: LATS suppresses mTORC1 activity to directly coordinate Hippo and mTORC1 pathways in gr
The Hippo and mammalian target of rapamycin complex 1 (mTORC1) pathways are the two predominant growth-control pathways that dictate...
Journal Club: An AMPK–caspase-6 axis controls liver damage in nonalcoholic steatohepatitis
Liver disease defect identified The energy sensor adenosine monophosphate–activated protein kinase (AMPK) is implicated in liver damage...
Journal Club: Metabolites released from apoptotic cells act as tissue messengers
Caspase-dependent apoptosis accounts for approximately 90% of homeostatic cell turnover in the body1, and regulates inflammation, cell...
Journal Club: Zika Virus Targets Glioblastoma Stem Cells through a SOX2-Integrin αvβ5 Axis
Highlights ZIKV preferentially infects glioblastoma stem cells (GSCs) rather than neural precursor cells ZIKV kills SOX2 + cells from a...
Highlight: Prix Jeune Talent France-Chine pour Nicolas
Nicolas has received today Prix Jeune Talent France-Chine from Pôle Enseignement Supérieur, Recherche et Innovation Ambassade de France...
Journal Club: AMPK, a Regulator of Metabolism and Autophagy, Is Activated by Lysosomal Damage via a
Lysosomal damage activates AMPK, autophagy, and metabolic and antimicrobial responses Galectin 9 transduces damage signal to ubiquitin...
Journal Club: GRK2 suppresses lymphomagenesis by inhibiting the MALT1 proto-oncoprotein
Antigen receptor–dependent (AgR-dependent) stimulation of the NF-κB transcription factor in lymphocytes is a required event during...
Journal Club: Gliomas Interact with Non-glioma Brain Cells via Extracellular Vesicles
Highlights Distinct types of gliomas interact with different sets of brain cells Glioma cells use extracellular vesicles to achieve the...