Signaling in Oncogenesis, Angiogenesis, and Permeability

Nature volume 585, pages283–287(2020) Abstract The risk of cancer and associated mortality increases substantially in humans from the age...

Highlights Tissue acidification is a major chemical hallmark of the tumor microenvironment PRL-expressing cells can grow in an acidic...

Breast cancer brain metastases (BCBM) have a 5-20 year latency and account for 30% of mortality; however, mechanisms governing adaptation...

Cancer cells, including melanoma cells, often metastasize regionally through the lymphatic system before metastasizing systemically...

https://www-nature-com.proxy.insermbiblio.inist.fr/articles/s41388-020-01420-x?fbclid=IwAR0LnEeJSj2pWuCpEzzrlD3Fcp5hk9o_UrqQZiwslHA_kQn1G...

Here is our perspective in Cell Cycle on Lysosomes in Glioblastoma.

Highlights • Non-cleavable caspase-8 (caspase-8 DA) causes inflammation, blocked by necroptosis • Inflammation in Casp8DA/DAMlkl−/− mice...

Highlights A high level of DGAT1 is associated with poor survival in individuals with GBM DGAT1 prevents lipotoxicity in GBM by promoting...

Highlights Soluble human ACE2 can inhibit SARS-CoV-2 infections SARS-CoV-2 can directly infect human blood vessel and kidney organoids...