Journal Club: Tumour exosomal CEMIP protein promotes cancer cell colonization in brain metastasis
Nature Cell Biol 2019 The development of effective therapies against brain metastasis is currently hindered by limitations in our...


Journal Club:Cell Lineage-Based Stratification for Glioblastoma
Cancer Cell 2020 Highlights  • Tumor suppressor loss in NSCs and OLCs generate distinct murine GBM subtypes • Human GBM subtypes...


Event: Fondation ARC JJC2020
Follow the on-line event with An Thys, Katie Jacobs, and Sara Rosinska


Journal Club: β-Coronaviruses Use Lysosomes for Egress Instead of the Biosynthetic Secretory Pathway
Cell 2020 Highlights  • β-Coronaviruses do not use the biosynthetic secretory pathway to egress • β-Coronaviruses traffic to lysosomes...


Journal Club: cAbl Inhibition Activates TFEB and Promotes Cellular Clearance in a Lysosomal Disorder
iScience 2020 Summary The  transcription factor EB (TFEB) has emerged as a master regulator of  lysosomal biogenesis, exocytosis, and...


Event: Welcome Fiorella!
Fiorella graduates from Universidad Austral, Buenos Aires, Argentina, where she explored  the implications of hyaluronan and its chemical...
Journal Club: Decellularized extracellular matrix scaffolds identifyfull-length collagen VI...
Science Advances  21 Oct 2020 Abstract The  extracellular matrix (ECM), a major component of the tumor  microenvironment, promotes local...
Journal Club: Neutrophil-induced ferroptosis promotes tumor necrosis in glioblastoma progression
Nature Communications  volume 11, Article number: 5424 (2020) Abstract Tumor  necrosis commonly exists and predicts poor prognoses in...


Journal Club: A Non-canonical PDK1-RSK Signal Diminishes Pro-caspase-8-Mediated Necroptosis Blockade
Mol Cell 2020 Summary Necroptosis induction in vitro  often requires caspase-8 (Casp8) inhibition by zVAD because pro-Casp8  cleaves RIP1...

