cancer research lab in Nantes

Journal Club: Denisovan, modern human and mouse TNFAIP3 alleles tune A20 phosphorylation and immunit

Resisting and tolerating microbes are alternative strategies to survive infection, but little is known about the evolutionary mechanisms...

Journal Club: DDX3X acts as a live-or-die checkpoint in stressed cells by regulating NLRP3 inflammas

The cellular stress response has a vital role in regulating homeostasis by modulating cell survival and death. Stress granules are...

Event: our work on Necroptosis highlighted by CNRS-INSB

Silence, on meurt ! La Pannexine-1 limite la production de cytokines proinflammatoires associée à la nécroptose...

Journal Club: Selective autophagy maintains centrosome integrity and accurate mitosis by turnover of

The centrosome is the master orchestrator of mitotic spindle formation and chromosome segregation in animal cells. Centrosome...

Journal Club: Imaging flow cytometry facilitates multiparametric characterization of extracellular v

Cells release heterogeneous nano-sized vesicles either as exosomes, being derived from endosomal compartments, or through budding from...

Highlight: Carolina laureate of Fondation de France grant!

Congrats to Carolina for getting a post-doctoral funding by Fondation de France

Journal Club: A bioprinted human-glioblastoma-on-a-chip for the identification of patient-specific r

Patient-specific ex vivo models of human tumours that recapitulate the pathological characteristics and complex ecology of native tumours...

Highlight: Pannexin‐1 limits the production of proinflammatory cytokines during necroptosis

On Line Abstract The activation of mixed lineage kinase‐like (MLKL) by receptor‐interacting protein kinase‐3 (RIPK3) controls the...

Event: O'Tablo Univ Nantes

JournalClub: Endothelial cells promote 3D invasion of GBM by IL-8-dependent induction of cancer stem

Rapid growth and perivascular invasion are hallmarks of glioblastoma (GBM) that have been attributed to the presence of cancer stem-like...