Journal Club: NF-κB c-Rel Is Crucial for the Regulatory T Cell Immune Checkpoint in Cancer
Highlights NF-κB c-Rel regulates the transcriptional landscape of activated Tregs c-Rel activity in Tregs restricts anti-tumor responses...
Journal Club: Hypoxic Induction of Vasorin Regulates Notch1 Turnover to Maintain Glioma Stem-like Ce
Highlights Vasorin maintains glioma stem-like cells GSCs) in the hypoxic niche HIF1α/STAT3 co-activator complex induces Vasorin...
Research Highlight: Temozolomide Affects Extracellular Vesicles Released by Glioblastoma Cells
Highlights Blood of brain tumour patients contains more circulating extracellular vesicles. Release of extracellular vesicles is enhanced...
JournalClub: OTUD4 Is a Phospho-Activated K63 Deubiquitinase that Regulates MyD88-Dependent Signalin
Highlights OTUD4 phosphorylation activates a K63-specific deubiquitinase activity OTUD4 K63 deubiquitinase activity requires a...
Highlight: Read Gwennan's portrait on the Fondation de France website
https://www.fondationdefrance.org/fr/tous-concernes-tous-mobilises#temoignages
Journal Club: Dendritic cells enter lymph vessels by hyaluronan-mediated docking to the endothelial
Trafficking of tissue dendritic cells (DCs) via lymph is critical for the generation of cellular immune responses in draining lymph nodes...
Journal Club: Hypothalamic stem cells control ageing speed partly through exosomal miRNAs
It has been proposed that the hypothalamus helps to control ageing, but the mechanisms responsible remain unclear. Here we develop...