Journal Club: A Method for the Acute and Rapid Degradation of Endogenous Proteins
Highlights Trim-Away is a widely applicable method to degrade endogenous proteins Target proteins do not need to be modified before...
Journal Club: Fatty Acid Synthase induced S6Kinase facilitates USP11-eIF4B complex formation for sus
Altered lipid metabolism and aberrant protein translation are strongly associated with cancerous outgrowth; however, the inter-regulation...
Research Highlight: Apelin, the Devil Inside Brain Tumors
Apelin, the Devil Inside Brain Tumors Elizabeth Harford-Wright, Julie Gavard Abstract Glioblastoma multiforme are mortifying brain tumors...
Journal Club: NF-κB c-Rel Is Crucial for the Regulatory T Cell Immune Checkpoint in Cancer
Highlights NF-κB c-Rel regulates the transcriptional landscape of activated Tregs c-Rel activity in Tregs restricts anti-tumor responses...
Journal Club: Hypoxic Induction of Vasorin Regulates Notch1 Turnover to Maintain Glioma Stem-like Ce
Highlights Vasorin maintains glioma stem-like cells GSCs) in the hypoxic niche HIF1α/STAT3 co-activator complex induces Vasorin...
Research Highlight: Temozolomide Affects Extracellular Vesicles Released by Glioblastoma Cells
Highlights Blood of brain tumour patients contains more circulating extracellular vesicles. Release of extracellular vesicles is enhanced...
JournalClub: OTUD4 Is a Phospho-Activated K63 Deubiquitinase that Regulates MyD88-Dependent Signalin
Highlights OTUD4 phosphorylation activates a K63-specific deubiquitinase activity OTUD4 K63 deubiquitinase activity requires a...
Highlight: Read Gwennan's portrait on the Fondation de France website
https://www.fondationdefrance.org/fr/tous-concernes-tous-mobilises#temoignages