JournalClub: Treatment of a metabolic liver disease by in vivo genome base editing in adult mice
CRISPR–Cas-based genome editing holds great promise for targeting genetic disorders, including inborn errors of hepatocyte metabolism....


Journal Club: The RAB11A-Positive Compartment Is a Primary Platform for Autophagosome Assembly Media
RAB11A binds WIPI2 via a conserved RAB11-binding domain and regulates autophagy Proteins regulating autophagosome formation localize on...


Event: Welcome Simon Martin for his PhD studies @LabSoap
Simon starts his PhD studies under the auspices of Fondation pour la Recherche Medicale to explore intercellular communication in the...
Journal Club: TAK1 activation of alpha-TAT1 and microtubule hyperacetylation control AKT signaling a
Acetylation of microtubules (MT) confers mechanical stability necessary for numerous functions including cell cycle and intracellular...


Journal Club: PIP5 Kinases Regulate Membrane Phosphoinositide and Actin Composition for Targeted Gra
Highlights Immune synapse formation triggers rapid changes in the membrane composition and charge PIP5K is a molecular sensor of TCR...
Journal Club: A tension-mediated glycocalyx-integrin feedback loop promotes mesenchymal-like gliobla
Glioblastoma multiforme (GBMs) are recurrent lethal brain tumours. Recurrent GBMs often exhibit mesenchymal, stem-like phenotypes that...


Event: 3rd International Conference on Stem Cells, Development and Cancer
Connecting new ideas in Developmental, Adult and Cancer Stem Cell Biology. The 3rd International Conference on Stem Cells, Development...
OTULIN limits cell death and inflammation by deubiquitinating LUBAC
OTULIN (OTU deubiquitinase with linear linkage specificity) removes linear polyubiquitin from proteins that have been modified by LUBAC...
Journal Club: A multiprotein supercomplex controlling oncogenic signalling in lymphoma
B cell receptor (BCR) signalling has emerged as a therapeutic target in B cell lymphomas, but inhibiting this pathway in diffuse large B...