Journal Club: Hypoxic Induction of Vasorin Regulates Notch1 Turnover to Maintain Glioma Stem-like Ce
Highlights Vasorin maintains glioma stem-like cells GSCs) in the hypoxic niche HIF1α/STAT3 co-activator complex induces Vasorin...
Research Highlight: Temozolomide Affects Extracellular Vesicles Released by Glioblastoma Cells
Highlights Blood of brain tumour patients contains more circulating extracellular vesicles. Release of extracellular vesicles is enhanced...
JournalClub: OTUD4 Is a Phospho-Activated K63 Deubiquitinase that Regulates MyD88-Dependent Signalin
Highlights OTUD4 phosphorylation activates a K63-specific deubiquitinase activity OTUD4 K63 deubiquitinase activity requires a...
Highlight: Read Gwennan's portrait on the Fondation de France website
https://www.fondationdefrance.org/fr/tous-concernes-tous-mobilises#temoignages
Journal Club: Dendritic cells enter lymph vessels by hyaluronan-mediated docking to the endothelial
Trafficking of tissue dendritic cells (DCs) via lymph is critical for the generation of cellular immune responses in draining lymph nodes...
Journal Club: Hypothalamic stem cells control ageing speed partly through exosomal miRNAs
It has been proposed that the hypothalamus helps to control ageing, but the mechanisms responsible remain unclear. Here we develop...
Journal Club: A major chromatin regulator determines resistance of tumor cells to T cell–mediated ki
Many human cancers are resistant to immunotherapy for reasons that are poorly understood. We used a genome-scale CRISPR/Cas9 screen to...