JournalClub: EGF receptor kinase suppresses ciliogenesis through activation of USP8 deubiquitinase
Ciliogenesis is generally inhibited in dividing cells, however, it has been unclear which signaling cascades regulate the phenomenon....


JournalClub: Inhibition of TRF1 Telomere Protein Impairs Tumor Initiation and Progression in Gliobla
TRF1 expression is increased in both human and mouse GBM TRF1 inhibition impairs GBM initiation and progression in different mouse models...
Journal Club: LUBAC-synthesized linear ubiquitin chains restrict cytosol-invading bacteria by activa
Cell-autonomous immunity relies on the ubiquitin coat surrounding cytosol-invading bacteria functioning as an 'eat-me' signal for...


Event: Cancer Research UK, Brain Tumour Conference 2018
Katie's poster presentation :-)


Highlight: Fondation pour la Recherche Médicale
Our team is now labelled FRM team 2018-21 Thanks for this great support!


Event: ISEV 2018, Barcelona
Gwennan's poster @ISEV2018 !
Journal Club: SHANK proteins limit integrin activation by directly interacting with Rap1 and R-Ras.
A paper from #IvaskaLab Abstract SHANK3, a synaptic scaffold protein and actin regulator, is widely expressed outside of the central...
Journal Club: Pharmacological activation of REV-ERBs is lethal in cancer and oncogene-induced senes
Gabriele Sully et al The circadian clock imposes daily rhythms in cell proliferation, metabolism, inflammation and DNA damage...


Highlight: Welcome to Andrea Bello for his training
Andrea Bello is Master1 student @UnivAngers. He will explore the cellular functions of Deubiquitylating Ligase CYLD