

Event: SOAP-treat Part II
Coming Up Soon, Friday the 21st!!!!
Journal Club: The lysosomal GPCR-like protein GPR137B regulates Rag and mTORC1 localization and acti
Cell growth is controlled by a lysosomal signalling complex containing Rag small GTPases and mammalian target of rapamycin complex 1...
Journal Club: LUBAC controls chromosome alignment by targeting CENP-E to attached kinetochores
Faithful chromosome segregation requires proper chromosome congression at prometaphase and dynamic maintenance of the aligned chromosomes...
JournalClub: TRIM27 mediates STAT3 activation at retromer-positive structures to promote colitis and
STAT3 is a transcription factor that plays central roles in various physiological processes and its deregulation results in serious...


Highlight: CYLD Regulates Centriolar Satellites Proteostasis by Counteracting the E3 Ligase MIB1
A subset of CYLD is found at the centriolar satellites CYLD maintains the proteostasis of the centriolar satellites CYLD removes...
Journal Club: HIV-1 remission following CCR5Δ32/Δ32 haematopoietic stem-cell transplantation
A cure for HIV-1 remains unattainable as only one case has been reported, a decade ago1,2. The individual—who is known as the ‘Berlin...
Journal Club: Extracellular vesicle-packaged HIF-1α-stabilizing lncRNA from tumour-associated macrop
Metabolic reprogramming is a hallmark of cancer. Here, we demonstrate that tumour-associated macrophages (TAMs) enhance the aerobic...
Journal Club: Deubiquitinase USP10 regulates Notch signaling in the endothelium
Notch signaling is a core patterning module for vascular morphogenesis that codetermines the sprouting behavior of endothelial cells...
Journal Club: A NIK–SIX signalling axis controls inflammation by targeted silencing of non-canonical
The non-canonical NF-κB signalling cascade is essential for lymphoid organogenesis, B cell maturation, osteoclast differentiation, and...