Signaling in Oncogenesis, Angiogenesis, and Permeability

Pre-prints are amazing!!! https://www.biorxiv.org/content/10.1101/582221v1.article-metrics

Cyclic GMP-AMP (cGAMP) synthase (cGAS) detects infections or tissue damage by binding to microbial or self DNA in the cytoplasm1. Upon...

The presence of disseminated tumour cells (DTCs) in bone marrow is predictive of poor metastasis-free survival of patients with breast...

Highlights LPS treatment causes a decrease in HBP activity and protein O-GlcNAcylation OGT deficiency increases activation of innate...

Highlights Pacer is a regulator of hepatic autophagy and liver homeostasis Pacer is directly phosphorylated by mTORC1 under nutrient-rich...

First Pre-Print of the Lab !! doi: https://doi.org/10.1101/537753

Abstract: Exosomes, a type of small extracellular vesicles (sEVs), derived from multivesicular bodies (MVBs), mediate cell-to-cell...

The increasing prevalence of diabetes has resulted in a global epidemic1. Diabetes is a major cause of blindness, kidney failure, heart...

The linear ubiquitin chain assembly complex (LUBAC), composed of HOIP, HOIL-1 and SHARPIN, is required for optimal TNF-mediated gene...