Journal Club: LUBAC accelerates B-cell lymphomagenesis by conferring B cells resistance to genotoxic
Key Points LUBAC accelerates B-cell lymphomagenesis through protection of DNA damage-induced apoptosis, thereby promoting AID-mediated...
Journal Club: Selective inhibition of cancer cell self-renewal through a Quisinostat-histone H1.0 ax
Abstract __________________________________________________________________________________________________________ Continuous cancer...
Journal Club: The HOIL-1L ligase modulates immune signalling and cell death via monoubiquitination o
Abstract The linear ubiquitin chain assembly complex (LUBAC), which consists of HOIP, SHARPIN and HOIL-1L, promotes NF-κB activation and...
Journal Club: Wnt-mediated endothelial transformation into mesenchymal stem cell–like cells induces
Endothelial transformation in glioblastoma Glioblastoma (GBM) is one of the most aggressive brain tumors. GBM is characterized by...
Journal Club: Small extracellular vesicles from human adipose-derived stem cells attenuate cartilage
ABSTRACT Osteoarthritis (OA) is a chronic degenerative disease of articular cartilage that is the most common joint disease worldwide....
Journal Club: Caspase-6 Is a Key Regulator of Innate Immunity, Inflammasome Activation, and Host Def
Abstract Caspases regulate cell death, immune responses, and homeostasis. Caspase-6 is categorized as an executioner caspase but shows...
